| IVIG- responsive multiple cranial neuropathy: a pharyngo-facial variant of Guillain-Barr? syndrome. | |
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MedLine Citation:
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PMID: 20120214 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a case with symptoms of facial swelling, bilateral facial paralysis, dysphagia and aspiration. On electrophysiological studies, the right facial nerve was not excitable. The left facial nerve compound muscle action potential (CMAP) amplitude was severely dispersed and latency was mildly prolonged, consistent with demyelination. Cerebrospinal fluid examinations were normal. Anti-ganglioside antibodies and tumor markers were negative. Bickerstaff brainstem encephalitis, stroke, diabetes mellitus, vasculitis, sarcoidosis, Sj?gren's syndrome, Melkersson-Rosenthal Syndrome, trauma, infectious diseases, toxicity, neoplasm, facial onset sensory and motor neuronopathy (FOSMN) and other degenerative diseases were excluded. Intravenous immunoglobulin therapy resolved symptoms of lower cranial nerve dysfunction. Clinically incomplete improvement of bilateral facial paralysis was observed. We conclude that IVIg therapy may improve the symptoms of multiple cranial nerve palsies due to pharyngo-facial variant of Guillain-Barr? syndrome. |
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Authors:
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Isin Unal-Cevik; Mehmet Zulkuf Onal; Zeki Odabasi; Ersin Tan |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Acta neurologica Belgica Volume: 109 ISSN: 0300-9009 ISO Abbreviation: Acta Neurol Belg Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2010-02-02 Completed Date: 2010-03-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0247035 Medline TA: Acta Neurol Belg Country: Belgium |
Other Details:
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Languages: eng Pagination: 317-21 Citation Subset: IM |
Affiliation:
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Ufuk University, Faculty of Medicine, Department of Neurology, Ankara, Turkey. isin.unalcevik@gmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged, 80 and over Cranial Nerve Diseases / diagnosis*, physiopathology, therapy* Facial Nerve / physiopathology Facial Paralysis / physiopathology Female Glossopharyngeal Nerve / physiopathology Guillain-Barre Syndrome / diagnosis*, physiopathology, therapy* Humans Immunoglobulins, Intravenous / therapeutic use* Neural Conduction / physiology Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulins, Intravenous |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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