| IVF twins have similar obstetric and neonatal outcome as spontaneously conceived twins: a prospective follow-up study. | |
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MedLine Citation:
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PMID: 20638334 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Studies comparing the outcome of spontaneous versus IVF twin pregnancies report heterogeneous results. This may depend on differences in the studied populations and/or in the management approach to twin pregnancy. The aim of the present study was to compare both maternal and perinatal outcomes in dichorionic diamniotic twin pregnancies who where spontaneously conceived or originated by successful homologous IVF. In order to get homogeneous observations, monochorionic twin pregnancies and triplet pregnancies were excluded. Moreover, to avoid any possible bias deriving from differences in the obstetric management, all pregnancies were managed by the same team applying fixed obstetric protocols. The study included 223 twin pregnancies, 84 conceived by IVF and 139 spontaneously conceived. Overall, maternal and perinatal outcomes were similar in the two groups: no significant differences were observed as far as gestational age at delivery, birthweight, perinatal morbidity and mortality, and rate of malformations were concerned. The rate of Caesarean section was slightly, but not significantly, higher in IVF pregnancies. In conclusion, the outcome of IVF twin pregnancies is comparable to that of spontaneously conceived twin pregnancies, provided that the same management criteria are applied. |
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Authors:
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Elena Vasario; Valentina Borgarello; Carlotta Bossotti; Enrico Libanori; Marilisa Biolcati; Silvana Arduino; Rita Spinelli; Luisa Delle Piane; Alberto Revelli; Tullia Todros |
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Publication Detail:
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Type: Comparative Study; Journal Article; Twin Study Date: 2010-04-22 |
Journal Detail:
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Title: Reproductive biomedicine online Volume: 21 ISSN: 1472-6491 ISO Abbreviation: Reprod. Biomed. Online Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-30 Completed Date: 2010-12-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101122473 Medline TA: Reprod Biomed Online Country: Netherlands |
Other Details:
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Languages: eng Pagination: 422-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Division of Maternal-Fetal Medicine, Department of Gynecological and Obstetrical Sciences, University of Turin, S. Anna Hospital, Turin, Italy. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Birth Weight Cesarean Section Clinical Protocols Female Fertilization in Vitro / adverse effects* Follow-Up Studies Humans Infant, Newborn Pregnancy Pregnancy Outcome Pregnancy, Multiple* Premature Birth / etiology Prospective Studies Twins, Dizygotic* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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