Document Detail

IVF pregnancy after induction of an ovulatory endogenous gonadotrophin surge using an LHRH agonist nasal spray.
MedLine Citation:
PMID:  2118545     Owner:  NLM     Status:  MEDLINE    
A successful human twin IVF pregnancy is reported after using a single 50 micrograms dose of LHRH agonist nasal spray (Buserelin) to induce an ovulatory endogenous gonadotrophin surge 34 h prior to oocyte collection. The couple had 10 years of primary male factor infertility, associated with significant anti-sperm antibodies. The clinical features and endocrine profile are presented.
B Bentick; R W Shaw; C A Iffland; G Burford; A Bernard
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  5     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1990 Jul 
Date Detail:
Created Date:  1990-10-09     Completed Date:  1990-10-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  570-2     Citation Subset:  IM    
Academic Department of Obstetrics and Gynaecology, Royal Free Hospital, London, UK.
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MeSH Terms
Administration, Intranasal
Buserelin / administration & dosage,  therapeutic use*
Estradiol / blood
Fertilization in Vitro*
Follicle Stimulating Hormone / blood
Infertility, Male / immunology,  therapy*
Luteinizing Hormone / blood
Ovulation Induction*
Progesterone / blood
Spermatozoa / immunology
Reg. No./Substance:
50-28-2/Estradiol; 57-83-0/Progesterone; 57982-77-1/Buserelin; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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