| IVF conversion to IUI in poor responders: an observational study. | |
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MedLine Citation:
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PMID: 20499076 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The purpose of this study was to evaluate the significance of converting an IVF stimulation cycle with poor ovarian response to an IUI cycle. METHODS: Between January and December 2007, 47 cycles of IVF conversion to IUI were retrospectively studied in 44 infertile women who had a low response to ovarian hyperstimulation for IVF. Patients' characteristics, ovarian stimulation, and ovarian response and outcome were collected and compared with those of 41 women undergoing ovum pickup for IVF with poor ovarian response (n = 44 cycles) in the same period. RESULTS: Women in the conversion group had slightly lower ovarian reserve, shorter stimulation with higher rFSH doses, lower peak estradiol and fewer mature follicles than in the IVF group. Pregnancy rates were comparable in both groups, though clinical pregnancy rate tended to be higher in the conversion group than in the IVF group. CONCLUSIONS: Thus, pregnancy rate in the conversion group compares favourably with IVF outcome in such circumstances. This means that IVF conversion to IUI in poor responders who are suitable for IUI is a valuable alternative that should be considered in their management. |
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Authors:
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Thomas Freour; Sophie Dubourdieu; Sophie Mirallie; Marie Laure Langlois; Miguel Jean; Paul Barrière |
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Publication Detail:
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Type: Evaluation Studies; Journal Article Date: 2010-05-25 |
Journal Detail:
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Title: Archives of gynecology and obstetrics Volume: 282 ISSN: 1432-0711 ISO Abbreviation: Arch. Gynecol. Obstet. Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-07 Completed Date: 2011-01-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8710213 Medline TA: Arch Gynecol Obstet Country: Germany |
Other Details:
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Languages: eng Pagination: 445-9 Citation Subset: IM |
Affiliation:
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Biologie et Médecine du développement et de la Reproduction, Hopital Mere et Enfant, CHU de Nantes, Nantes Cedex 3, France. thomas.freour@chu-nantes.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Estradiol / blood Female Fertilization in Vitro* Follicle Stimulating Hormone / blood France Gonadotropin-Releasing Hormone / blood Hospitals, University Humans Infertility / therapy* Insemination, Artificial / methods* Male Ovarian Follicle Ovulation Induction* Pregnancy Pregnancy Rate Retrospective Studies Sperm Count Sperm Injections, Intracytoplasmic Sperm Motility Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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33515-09-2/Gonadotropin-Releasing Hormone; 50-28-2/Estradiol; 9002-68-0/Follicle Stimulating Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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