Document Detail

IV tPA for acute ischemic stroke: results of the first 101 patients in a community practice.
MedLine Citation:
PMID:  16148738     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Reviews of the use of intravenous tissue type plasminogen activator (IV tPA) for acute stroke in community hospitals have raised questions regarding its safe use in community practice settings outside major academic stroke centers. Many neurologists have been reluctant to use IV tPA in their practices. We therefore analyzed the experience of this community neurology practice in treating acute strokes with IV tPA. REVIEW SUMMARY: We retrospectively reviewed our treatment experience for 101 patients given IV tPA in one community neurology practice in 3 Cleveland-area hospitals between 1997 and 2003. Symptomatic hemorrhage occurred in 2 of 101 patients who received IV tPA. Median National Institutes of Health Stroke Scale (NIHSS) was 10.8 pretreatment, 3 at 24 hours, and 2.1 on hospital discharge. IV tPA treatment rate increased from 4.7% to 10.3% between 1999 and 2003. CONCLUSION: IV tPA for acute ischemic stroke can be given safely and effectively by physicians in an independent neurology practice in the community hospital setting.
Arthur P Dick; Janet Straka
Related Documents :
12944188 - Fast-track open transperitoneal nephrectomy.
17724908 - Heat stroke complicated by liver failure and hyperbilirubinaemia--a case report.
17430308 - Two case reports of oral ulcers with lamotrigine several weeks after oxcarbazepine with...
14604128 - Code gray--an organized approach to inpatient stroke.
11171778 - Guidelines and critical pathways for severe hospital-acquired pneumonia.
21905438 - Ama focuses on graduate education requirements.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The neurologist     Volume:  11     ISSN:  1074-7931     ISO Abbreviation:  Neurologist     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-09-08     Completed Date:  2005-12-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9503763     Medline TA:  Neurologist     Country:  United States    
Other Details:
Languages:  eng     Pagination:  305-8     Citation Subset:  IM    
Arthur P. Dick Neurology, Inc., Lakewood, OH 44107, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acute Disease
Aged, 80 and over
Aging / physiology
Anticoagulants / administration & dosage,  therapeutic use
Hospitals, Community
Injections, Intravenous
International Normalized Ratio
Middle Aged
Plasminogen Activators / administration & dosage,  adverse effects,  therapeutic use*
Retrospective Studies
Stroke / drug therapy*
Tissue Plasminogen Activator / administration & dosage,  adverse effects,  therapeutic use*
Treatment Outcome
Warfarin / administration & dosage,  therapeutic use
Reg. No./Substance:
0/Anticoagulants; 81-81-2/Warfarin; EC 3.4.21.-/Plasminogen Activators; EC Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Multiple sclerosis and Hashimoto thyroiditis: two cases.
Next Document:  Axotomized bulbospinal neurons express c-Jun after cervical spinal cord injury.