Document Detail


IV tPA for acute ischemic stroke: results of the first 101 patients in a community practice.
MedLine Citation:
PMID:  16148738     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Reviews of the use of intravenous tissue type plasminogen activator (IV tPA) for acute stroke in community hospitals have raised questions regarding its safe use in community practice settings outside major academic stroke centers. Many neurologists have been reluctant to use IV tPA in their practices. We therefore analyzed the experience of this community neurology practice in treating acute strokes with IV tPA. REVIEW SUMMARY: We retrospectively reviewed our treatment experience for 101 patients given IV tPA in one community neurology practice in 3 Cleveland-area hospitals between 1997 and 2003. Symptomatic hemorrhage occurred in 2 of 101 patients who received IV tPA. Median National Institutes of Health Stroke Scale (NIHSS) was 10.8 pretreatment, 3 at 24 hours, and 2.1 on hospital discharge. IV tPA treatment rate increased from 4.7% to 10.3% between 1999 and 2003. CONCLUSION: IV tPA for acute ischemic stroke can be given safely and effectively by physicians in an independent neurology practice in the community hospital setting.
Authors:
Arthur P Dick; Janet Straka
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The neurologist     Volume:  11     ISSN:  1074-7931     ISO Abbreviation:  Neurologist     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-09-08     Completed Date:  2005-12-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9503763     Medline TA:  Neurologist     Country:  United States    
Other Details:
Languages:  eng     Pagination:  305-8     Citation Subset:  IM    
Affiliation:
Arthur P. Dick Neurology, Inc., Lakewood, OH 44107, USA. ArthurPDick@netscape.net
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Aged
Aged, 80 and over
Aging / physiology
Anticoagulants / administration & dosage,  therapeutic use
Female
Hospitals, Community
Humans
Injections, Intravenous
International Normalized Ratio
Male
Middle Aged
Plasminogen Activators / administration & dosage,  adverse effects,  therapeutic use*
Retrospective Studies
Stroke / drug therapy*
Tissue Plasminogen Activator / administration & dosage,  adverse effects,  therapeutic use*
Treatment Outcome
Warfarin / administration & dosage,  therapeutic use
Chemical
Reg. No./Substance:
0/Anticoagulants; 81-81-2/Warfarin; EC 3.4.21.-/Plasminogen Activators; EC 3.4.21.68/Tissue Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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