| IL-1β activation as a response to metabolic disturbances. | |
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MedLine Citation:
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PMID: 21035753 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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IL-1β is a major regulator of islet inflammation in type 2 diabetes. Several factors contribute to the induction of islet-derived IL-1β, including glucose, free fatty acids, and leptin. A recent report in Nature Immunology (Masters et al., 2010) identifies amyloid polypeptide as an additional enhancer of IL-1β production. |
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Authors:
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Marc Y Donath; Marianne Böni-Schnetzler |
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Publication Detail:
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Type: Comment; Journal Article |
Journal Detail:
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Title: Cell metabolism Volume: 12 ISSN: 1932-7420 ISO Abbreviation: Cell Metab. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-11-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101233170 Medline TA: Cell Metab Country: United States |
Other Details:
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Languages: eng Pagination: 427-8 Citation Subset: - |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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University Hospital Basel, Switzerland. MDonath@uhbs.ch |
Export Citation:
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Descriptor/Qualifier:
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| Comments/Corrections | |
Comment On:
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Nat Immunol. 2010 Oct;11(10):897-904
[PMID:
20835230
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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