| An IL-6 link between obesity and cancer . | |
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MedLine Citation:
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PMID: 23277002 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Obesity is a growing epidemic all over the world that by virtue of inducation of a chronic, low-grade, and systemic inflammation leads to an increased risk of a number of diseases, including cancer. IL-6 an important cytokine in the increased risk to cancer in obese patients mainly because of its pro-inflammatory activitiy. Some data suggest that IL-6 might increase the risk of certain cancers such as those that originate from breast, liver, prostate, colon, and esophagus. A better understanding of the regulation and role of IL-6 in obesity-associated cancer is required to develop effective therapeutic approaches. |
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Authors:
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Sagar Ghosh; Keith Ashcraft |
Publication Detail:
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Type: Journal Article Date: 2013-01-01 |
Journal Detail:
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Title: Frontiers in bioscience (Elite edition) Volume: 5 ISSN: 1945-0508 ISO Abbreviation: Front Biosci (Elite Ed) Publication Date: 2013 |
Date Detail:
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Created Date: 2013-01-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101485240 Medline TA: Front Biosci (Elite Ed) Country: United States |
Other Details:
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Languages: eng Pagination: 461-78 Citation Subset: IM |
Affiliation:
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Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, 15355 Lambda Dr, San Antonio, TX-78245, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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