Document Detail

ICSI outcome in patients with transient azoospermia with initially motile or immotile sperm in the ejaculate.
MedLine Citation:
PMID:  15980009     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: In patients with transient azoospermia, few sperm may be found in the ejaculate. We investigated the outcome of ICSI in patients with transient azoospermia. METHODS: Records of patients with transient azoospermia referred during a 42 month period were reviewed. If only immotile sperm were found, the sample was incubated with 30% human serum albumin (HSA) before motility re-assessment. If still immotile, mechanical assessment of sperm viability was utilized. Study groups were: (A) motile sperm; (B) motility achieved by HSA; (C) no motility, but viability assessed by a mechanical technique; and (D) control group with sperm counts from 1 to 5 x 10(6)/ml. There were 57 couples (cycles) in the study group and 43 couples (cycles) in the control group. RESULTS: Age, days of stimulation and endometrial thickness were comparable among groups. In 29.8% of the cycles, only immotile sperm were found. Fertilization and cleavage rates were higher in groups A and D than in groups B and C. Clinical pregnancy rate/cycle and live birth rate/cycle were not different among groups. No congenital malformations were found in newborns. CONCLUSION: Fertilization and cleavage rates were lower in patients with initially immotile sperm compared with those with initially motile sperm and oligoasthenoteratozoospermia patients. Clinical pregnancy and viable pregnancy rates were not statistically different among groups, although when only immotile sperm were present both clinical pregnancy and live birth rate were lower in comparison with cycles with motile sperm.
J Tal; G Ziskind; Y Paltieli; Z Leibovitz; A Fishman; G Ohel; G Paz; N Lewit; I Calderon
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Publication Detail:
Type:  Journal Article     Date:  2005-06-24
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  20     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-08-11     Completed Date:  2005-10-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  England    
Other Details:
Languages:  eng     Pagination:  2584-9     Citation Subset:  IM    
IVF Unit, Department of Obstetrics and Gynecology, Bnai-Zion Medical Center and the Bruce Rappaport Faculty of Medicine, the Technion, Haifa, Israel.
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MeSH Terms
Infant, Newborn
Oligospermia / therapy*
Pregnancy Outcome*
Sperm Injections, Intracytoplasmic*
Sperm Motility*
Spermatozoa / pathology

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