Document Detail

Hysteroscopic endometrial ablation is an effective alternative to hysterectomy in women with menorrhagia and large uteri.
MedLine Citation:
PMID:  10924627     Owner:  NLM     Status:  MEDLINE    
STUDY OBJECTIVES: To examine the feasibility, safety, and outcome of hysteroscopic endometrial ablation, and to determine the volume of fluid absorbed during resection versus rollerball coagulation in women with menorrhagia and large uteri. DESIGN: Retrospective review (Canadian Task Force classification II-2). SETTING: University-affiliated teaching hospital. PATIENTS: Forty-two consecutive patients (mean +/- SD age 45.6 +/- 6 yrs) with uterine size greater than 12 weeks (cavity >12 cm). Intervention. Endometrial ablation; 26 (62%) women were pretreated to thin the endometrium. MEASUREMENTS AND MAIN RESULTS: Resection was performed in 27 patients (65%) and rollerball coagulation in 15 (35%). Ablation was successfully performed in all patients in a day surgery setting. Multiple regression analysis examined the relationship of uterine size, pretreatment, procedure, and duration of surgery to amount of glycine absorbed. Glycine absorption was higher with resection than with coagulation (p = 0.04). Fluid absorption correlated with type of procedure (r = 0.32, p = 0.04) but not with duration of the procedure, uterine size, or pretreatment. One patient with uterine fibroids and one with endometrial adenocarcinoma had hysterectomy. With follow-up of 39 (95%) of 41 women (excluding the one with adenocarcinoma) for 14 +/- 2 months, 38 (93%) were very satisfied. Thirty (73%) had amenorrhea, six (15%) had hypomenorrhea (<3 pads/day), and three (7%) had eumenorrhea (<10 pads/day). CONCLUSION: Hysteroscopic endometrial ablation may be a feasible, safe, and effective alternative to hysterectomy in women with menorrhagia and large uteri.
M A Eskandar; G A Vilos; F A Aletebi; I S Tummon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of the American Association of Gynecologic Laparoscopists     Volume:  7     ISSN:  1074-3804     ISO Abbreviation:  J Am Assoc Gynecol Laparosc     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2000-10-19     Completed Date:  2000-10-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9417443     Medline TA:  J Am Assoc Gynecol Laparosc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  339-45     Citation Subset:  IM    
Department of Obstetrics and Gynecology, St. Joseph's Health Center, 268 Grosvenor Street, London, Ontario, Canada.
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MeSH Terms
Electrocoagulation* / methods
Endometrium / surgery
Feasibility Studies
Glycine / therapeutic use
Menorrhagia / therapy*
Middle Aged
Retrospective Studies
Uterus / anatomy & histology
Reg. No./Substance:

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