| Hypoxic respiratory failure: etiology and outcomes at one referral center 2000 through 2005. | |
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MedLine Citation:
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PMID: 17443197 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: We calculated in a referral population of term and near-term infants with hypoxic respiratory failure (HRF) as a primary presenting problem the overall survival rate, the need for extracorporeal membrane oxygenation (ECMO) and the incidence of apparently irreversible disorders. STUDY DESIGN: All infants >or=36-week gestation admitted at <or=72 h of age from 2000 through 2005 were identified. The worst (highest) oxygen index (OI) was calculated and outcomes were noted. RESULTS: A total of 630 infants were reviewed and 315 infants were identified with primary diagnosis of HRF; four infants died before discharge. One hundred seventy-seven infants had OI <or=14; 71 had OI of 15 to 25; and 67 had OI of >25. A total of 32 infants received ECMO, including all four who died, two with histologic evidence of pulmonary malformations and two with septic shock. CONCLUSION: Term or near-term infants with isolated HRF are likely to survive, given the low incidence of pulmonary disorders not supportable by inhaled nitric oxide or ECMO. |
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Authors:
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W E Truog; G Kurth; B Haney; H W Kilbride |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2007-04-19 |
Journal Detail:
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Title: Journal of perinatology : official journal of the California Perinatal Association Volume: 27 ISSN: 0743-8346 ISO Abbreviation: J Perinatol Publication Date: 2007 Jun |
Date Detail:
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Created Date: 2007-05-24 Completed Date: 2007-07-20 Revised Date: 2007-12-03 |
Medline Journal Info:
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Nlm Unique ID: 8501884 Medline TA: J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 371-4 Citation Subset: IM |
Affiliation:
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Children's Mercy Hospitals and Clinics, Department of Pediatrics, Section of Neonatology, Kansas City, MO 64108, USA. wtruog@cmh.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Inhalation Extracorporeal Membrane Oxygenation / utilization Female Fetal Hypoxia / blood, epidemiology*, etiology, therapy Humans Infant, Newborn Intensive Care Units Male Medical Records Missouri / epidemiology Nitric Oxide / administration & dosage Oxygen / blood* Referral and Consultation / statistics & numerical data Respiratory Insufficiency / blood, complications, epidemiology*, therapy Retrospective Studies |
| Grant Support | |
ID/Acronym/Agency:
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R-01 70560//PHS HHS |
| Chemical | |
Reg. No./Substance:
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10102-43-9/Nitric Oxide; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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