Document Detail


Hypoxia in paranasal sinuses of patients with chronic sinusitis with or without the complication of nasal allergy.
MedLine Citation:
PMID:  12797588     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: In order to elucidate the pathogenesis of the radiologic opacity of the sinuses frequently observed in patients with allergic rhinitis, the mechanisms underlying their sinus mucosal swelling were studied clinically. MATERIAL AND METHODS: We confirmed the presence of hypoxia in inflamed sinuses and obstruction of the sinus ostium in operated patients with chronic sinusitis by digitally monitoring the oxygen tension. The possibility of radiologic sinus shadow was also investigated after transient obstruction of the natural ostium. RESULTS: The oxygen tension was significantly lower in inflamed than non-inflamed sinuses (p < 0.01), irrespective of the presence or absence of allergic rhinitis. In 54.5% of patients without sinusitis, transient obstruction of the middle meatus by gauze packing resulted in the appearance of a pathologic sinus shadow on radiograms obtained after septoplasty and turbinotomy. In both allergic and non-allergic rhinitis, thick opacity was the most frequently encountered pattern (p < 0.01). CONCLUSION: Our study revealed that in the absence of a primary allergic reaction in the sinus mucosa, blocking of the middle meatus and ostium by allergic swelling of the nasal mucosa may induce hypoxia and secondary mucosal swelling in the sinuses.
Authors:
Shoji Matsune; Motoko Kono; Dong Sun; Masato Ushikai; Yuichi Kurono
Related Documents :
22142508 - Acute energy compensation and macronutrient intake following exercise in active and ina...
22073428 - Non-exercise physical activity in agricultural and urban people.
1058748 - A roentgencephalometric investigation of the effect of adenoid removal upon selected me...
17185498 - Swallowing function and upper airway sensation in obstructive sleep apnea.
12839048 - Exercise capability and myocardial perfusion in chronic angina patients treated with en...
20151058 - Estimated right ventricular systolic pressure during exercise stress echocardiography i...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta oto-laryngologica     Volume:  123     ISSN:  0001-6489     ISO Abbreviation:  Acta Otolaryngol.     Publication Date:  2003 May 
Date Detail:
Created Date:  2003-06-11     Completed Date:  2003-09-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370354     Medline TA:  Acta Otolaryngol     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  519-23     Citation Subset:  IM    
Affiliation:
Department of Otolaryngology, Faculty of Medicine, Kagoshima University, Sakuragaoka, Kagoshima, Japan. shoji@med5.kufm.kagoshima-u.ac.jp
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Case-Control Studies
Female
Humans
Male
Maxillary Sinus / radiography
Maxillary Sinusitis / metabolism*,  radiography
Middle Aged
Nasal Mucosa / metabolism
Oxygen / metabolism*
Partial Pressure
Rhinitis, Allergic, Perennial / metabolism*,  radiography
Chemical
Reg. No./Substance:
7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Model experiment of benign paroxysmal positional vertigo mechanism using the whole membranous labyri...
Next Document:  Tumor necrosis factor increases MUC1 mRNA in cultured human nasal epithelial cells.