Document Detail


Hypoxia: developments in basic science, physiology and clinical studies.
MedLine Citation:
PMID:  22074075     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Airway management is primarily designed to avoid hypoxia, yet hypoxia remains the main ultimate cause of anaesthetic-related death and morbidity. Understanding some of the physiology of hypoxia is therefore essential as part of a 'holistic' approach to airway management. Furthermore, it is strategically important that national specialist societies dedicated to airway management do not only focus upon the technical aspects of airway management, but also embrace some of the relevant scientific questions. There has been a great deal of research into causation of hypoxia and the body's natural protective mechanisms and responses to it. This enables us to think of ways in which we might manipulate the cellular and molecular responses to confer greater protection against hypoxia-induced tissue injury. This article reviews some of those aspects.
Authors:
D S Ward; S B Karan; J J Pandit
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anaesthesia     Volume:  66 Suppl 2     ISSN:  1365-2044     ISO Abbreviation:  Anaesthesia     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-11-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  England    
Other Details:
Languages:  eng     Pagination:  19-268     Citation Subset:  AIM; IM    
Copyright Information:
© 2011 The Authors. Anaesthesia © 2011 The Association of Anaesthetists of Great Britain and Ireland.
Affiliation:
Professor of Anaesthesiology,  Associate Professor of Anaesthesiology, University of Rochester Medical Center, Rochester, New York, USA  Consultant Anaesthetist, Nuffield Department of Anaesthetics; John Radcliffe Hospital; Senior Lecturer, Nuffield Department of Clinical Neuroscience, University of Oxford, Oxford, UK.
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