Document Detail

Hypoxemia-orthodeoxia related to patent foramen ovale without pulmonary hypertension.
MedLine Citation:
PMID:  18790339     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Patent foramen ovale (PFO) is frequent but rarely associated with platypnea-orthodeoxia syndrome and with no pulmonary hypertension. MATERIALS AND METHODS: We performed a retrospective analysis of 12 consecutive patients with hypoxemia and PFO without increased pulmonary arterial pressure. The study was conducted at a single-center university hospital. We analyzed the patients' clinical records, gas exchange, contrast echocardiography studies, and survival. RESULTS: Twelve patients, aged 73.1 +/- 9.5 years, were diagnosed with PFO between 1993 and 2005. All patients experienced dyspnea and/or hypoxemia. Six right hemidiaphragmatic elevations were observed on radiography. The shunt was apparent in three patients using transthoracic echocardiography and in all patients using transesophageal echocardiography. The mean follow-up was 27.6 +/- 32.9 months. The PFO was closed in eight patients, six via percutaneous approach and two via surgery. CONCLUSION: PFO may be patent and responsible for hypoxemia without pulmonary hypertension. This condition is easily recognized with transesophageal echocardiography, leading in most cases to a percutaneous closure resulting in a dramatic correction of hypoxemia.
Anne Claire Toffart; Hélène Bouvaist; Virginie Feral; Dominique Blin; Christophe Pison
Related Documents :
1178809 - The haemolytic uraemic syndrome--a family study.
11411729 - Different patterns of silent cerebral infarct in patients with coronary artery disease ...
9468449 - Association of lipoprotein(a) levels and apolipoprotein(a) phenotypes with coronary hea...
6644959 - Systolic hypertension in the elderly. hemodynamic response to long-term thiazide diuret...
14684669 - Cardiovascular and renal risk assessment as a guide for treatment in primary hypertension.
6295149 - Long-term therapy of chronic mucocutaneous candidiasis with ketoconazole: experience wi...
15848719 - C2 and c0 values for monitoring cyclosporine therapy in stable heart transplant recipie...
3445879 - Airway hyperreactivity and menstrual cycle in asthmatic patients.
24216069 - Effects of omega-3 polyunsaturated fatty acid supplementation in patients with chronic ...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Heart & lung : the journal of critical care     Volume:  37     ISSN:  1527-3288     ISO Abbreviation:  Heart Lung     Publication Date:    2008 Sep-Oct
Date Detail:
Created Date:  2008-09-15     Completed Date:  2009-01-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0330057     Medline TA:  Heart Lung     Country:  United States    
Other Details:
Languages:  eng     Pagination:  385-9     Citation Subset:  AIM; IM    
Pôle Médecine Aiguë et Communautaire, Pneumologie, Centre Hospitalier Universitaire de Grenoble, Université de Grenoble, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged, 80 and over
Anoxia / diagnosis*,  etiology*,  surgery
Dyspnea / diagnosis,  etiology
Echocardiography, Transesophageal
Follow-Up Studies
Foramen Ovale, Patent / complications*,  diagnosis,  surgery
Hypertension, Pulmonary / etiology
Lung Neoplasms / complications,  surgery
Obesity / complications
Postoperative Complications
Pulmonary Gas Exchange
Rare Diseases
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Staphylococcus capitis prosthetic valve endocarditis: report of two rare cases and review of literat...
Next Document:  Electrocardiographic changes after shoulder arthroplasty.