Document Detail


Hypovolemic shock and contrast-enhanced computed tomography of the pancreas.
MedLine Citation:
PMID:  3726455     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of profound hemorrhagic hypovolemia on cardiac output and pancreatic blood flow was studied in pigs with the thermodilution method and microsphere technique. Approximately 30-40% of the circulating blood volume was withdrawn slowly during 5 h. Cardiac output and pancreatic blood flow decreased by 35% and 32%, respectively. The animals underwent contrast-enhanced computed tomography (CT) before hypovolemia and at 5 h after its onset. The changes in systemic and local blood flow were related to the contrast enhancement of the pancreas. In spite of profound hypovolemia and a significant decrease in pancreatic blood flow (p less than 0.005), the contrast enhancement remained normal. The results of the present study indicate that pancreatic hypoperfusion caused by hypovolemia does not affect the contrast enhancement of the pancreas in CT.
Authors:
P Nuutinen; L Kivisaari; A Lehtola; M Talja; C G Standertskjöld-Nordenstam; M Lempinen; T Schröder
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of gastroenterology     Volume:  21     ISSN:  0036-5521     ISO Abbreviation:  Scand. J. Gastroenterol.     Publication Date:  1986 May 
Date Detail:
Created Date:  1986-07-29     Completed Date:  1986-07-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0060105     Medline TA:  Scand J Gastroenterol     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  483-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Diatrizoate / analogs & derivatives*
Diatrizoate Meglumine / diagnostic use*
Hemodynamics
Pancreas / blood supply*,  radiography
Shock / physiopathology*
Swine
Tomography, X-Ray Computed*
Chemical
Reg. No./Substance:
117-96-4/Diatrizoate; 131-49-7/Diatrizoate Meglumine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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