| Hypotriacylglycerolemic and antiobesity properties of a new fermented tea product obtained by tea-rolling processing of third-crop green tea (Camellia sinensis) leaves and loquat (Eriobotrya japonica) leaves. | |
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MedLine Citation:
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PMID: 20699580 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We manufactured a new fermented tea by tea-rolling processing of third-crop green tea (Camellia sinensis) leaves and loquat (Eriobotrya japonica) leaves. The mixed fermented tea extract inhibited pancreatic lipase activity in vitro, and effectively suppressed postprandial hypertriacylglycerolemia in rats. Rats fed a diet containing 1% freeze-dried fermented tea extract for 4 weeks had a significantly lower liver triacylglycerol concentration and white adipose tissue weight than those fed the control diet lacking fermented tea extract. The activity of fatty acid synthase in hepatic cytosol markedly decreased in the fermented tea extract group as compared to the control group. The serum and liver triacylglycerol- and body fat-lowering effects of the mixed fermented tea extract were strong relative to the level of dietary supplementation. These results suggest that the new fermented tea product exhibited hypotriacylglycerolemic and antiobesity properties through suppression of both liver fatty acid synthesis and postprandial hypertriacylglycerolemia by inhibition of pancreatic lipase. |
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Authors:
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Kazunari Tanaka; Shizuka Tamaru; Shoko Nishizono; Yuji Miyata; Kei Tamaya; Toshiro Matsui; Takashi Tanaka; Yoshie Echizen; Ikuo Ikeda |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-08-07 |
Journal Detail:
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Title: Bioscience, biotechnology, and biochemistry Volume: 74 ISSN: 1347-6947 ISO Abbreviation: Biosci. Biotechnol. Biochem. Publication Date: 2010 |
Date Detail:
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Created Date: 2010-08-25 Completed Date: 2010-12-15 Revised Date: 2010-12-28 |
Medline Journal Info:
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Nlm Unique ID: 9205717 Medline TA: Biosci Biotechnol Biochem Country: Japan |
Other Details:
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Languages: eng Pagination: 1606-12 Citation Subset: IM |
Affiliation:
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Graduate School of Human Health Science, University of Nagasaki, Nagayo-cho, Nishisonogi-gun, Nagasaki, Japan. katanaka@sun.ac.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anti-Obesity Agents / isolation & purification, pharmacology* Camellia sinensis / chemistry* Dietary Supplements Eriobotrya / chemistry* Fermentation* Food Handling Hypolipidemic Agents / isolation & purification, pharmacology* Intra-Abdominal Fat / drug effects, metabolism Lipase / metabolism Liver / drug effects, metabolism Male Pancreas / drug effects, enzymology Plant Leaves / chemistry* Postprandial Period / drug effects Rats Rats, Sprague-Dawley Tea / chemistry* Triglycerides / blood* |
| Chemical | |
Reg. No./Substance:
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0/Anti-Obesity Agents; 0/Hypolipidemic Agents; 0/Tea; 0/Triglycerides; EC 3.1.1.3/Lipase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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