| Hypothyroidism and hypercalcemia: report of a case with a parathyroid adenoma and review of the literature. | |
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MedLine Citation:
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PMID: 918707 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A woman with hyperthyroidism, hypercalcemia, and a parathyroid adenoma is described. Various studies indicate that in hypothyroid subjects given an acute dose of calcium, the serum calcium levels remain elevated for longer periods than in control subjects. In part, this may be due to diminished bone uptake. Despite these studies which would tend to support the contention that hypothyroid patients "have a propensity to hypercalcemia" (Lowe et al), overt and significant hypercalcemia is unusual. Hypothyroidism is listed as a possible cause of hypercalcemia. This does not seem to be warranted by a review of the literature. The reference most often cited is that of Lowe et al. In their particular case, the hypercalcemia improved with thyroid replacement therapy. This also happened in our case. However, the measurement of IPTH levels led to the correct diagnosis. IPTH levels were not available at the time of Lowe's report and hyperparathyroidism was not completely excluded. Therefore, at this time, the reported association of hypercalcemia with adult hypothyroidism needs further examination to determine if this association is real. |
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Authors:
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T C Jones; J J Yium |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Southern medical journal Volume: 70 ISSN: 0038-4348 ISO Abbreviation: South. Med. J. Publication Date: 1977 Nov |
Date Detail:
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Created Date: 1977-12-29 Completed Date: 1977-12-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0404522 Medline TA: South Med J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1373-5 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenoma
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complications* Calcium / blood Female Humans Hypercalcemia / blood* Hypothyroidism / blood* Middle Aged Parathyroid Hormone / blood Parathyroid Neoplasms / complications* Thyrotropin / blood Thyroxine / blood |
| Chemical | |
Reg. No./Substance:
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0/Parathyroid Hormone; 7440-70-2/Calcium; 7488-70-2/Thyroxine; 9002-71-5/Thyrotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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