Document Detail

Hypothyroidism and autism spectrum disorders.
MedLine Citation:
PMID:  1577897     Owner:  NLM     Status:  MEDLINE    
Five children (three boys and two girls) with autism or autistic-like conditions are described. Three of them had congenital hypothyroidism and two had mothers who had probably been hypothyroid in pregnancy. It is suggested that hypothyroid hormone deficiency in early development might cause central nervous system damage such that autistic symptoms are likely to ensue. An alternative explanation might be autoimmune factors linking hypothyroidism and autism.
I C Gillberg; C Gillberg; S Kopp
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of child psychology and psychiatry, and allied disciplines     Volume:  33     ISSN:  0021-9630     ISO Abbreviation:  J Child Psychol Psychiatry     Publication Date:  1992 Mar 
Date Detail:
Created Date:  1992-06-10     Completed Date:  1992-06-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375361     Medline TA:  J Child Psychol Psychiatry     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  531-42     Citation Subset:  IM    
Department of Child and Adolescent Psychiatry, Child Neuropsychiatry Centre, Göteborg, Sweden.
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MeSH Terms
Autistic Disorder / etiology*,  genetics
Autoimmune Diseases / complications,  genetics
Central Nervous System Diseases / complications
Child, Preschool
Congenital Hypothyroidism*
Epilepsy / physiopathology
Hyperbilirubinemia / complications
Hypothyroidism / complications,  genetics
Infant, Newborn
Mental Retardation / physiopathology
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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