Document Detail


Hypothyroid myopathy with manifestations of Hoffman's syndrome and myasthenia gravis.
MedLine Citation:
PMID:  18279025     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although hypothyroid myopathy is seen frequently and the relationship with autoimmune hypothyroidism and myasthenia gravis is well known, specific forms of hypothyroid myopathy such as Hoffman's syndrome (HS) are rarely described. Here we describe a 40-year-old patient with Hashimoto thyroiditis showing symptoms and signs of two discrete forms of hypothyroid myopathy (HS and myasthenic syndrome) together. To our knowledge this is the first reported case with features of both of these syndromes. We discuss the diagnosis, speculate whether this patient may represent a unique form of hypothyroid myopathy, and report the 6-month follow-up of the patient both clinically and electrophysiologically.
Authors:
Hande Turker; Oytun Bayrak; Levent Gungor; Ahmet Yilmaz; Murat Terzi; Cuneyt M Turker; Musa K Onar; Hakki Kahraman
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Thyroid : official journal of the American Thyroid Association     Volume:  18     ISSN:  1050-7256     ISO Abbreviation:  Thyroid     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-02-18     Completed Date:  2008-04-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9104317     Medline TA:  Thyroid     Country:  United States    
Other Details:
Languages:  eng     Pagination:  259-62     Citation Subset:  IM    
Affiliation:
Ondokuzmayis University, Faculty of Medicine, Department of Neurology, and Gazi State Hospital, Department of Internal Medicine, Samsun, Turkey. handet@omu.edu.tr
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MeSH Terms
Descriptor/Qualifier:
Adult
Autoantibodies / blood
Diagnosis, Differential
Electromyography
Hashimoto Disease / blood,  complications*,  drug therapy,  physiopathology
Hormone Replacement Therapy
Humans
Male
Muscle Weakness
Muscular Atrophy / blood,  diagnosis*,  drug therapy,  etiology,  physiopathology
Myasthenia Gravis / blood,  diagnosis*,  drug therapy,  etiology,  physiopathology
Neural Conduction
Syndrome
Thyroid Function Tests
Thyroid Hormones / blood,  therapeutic use
Treatment Outcome
Chemical
Reg. No./Substance:
0/Autoantibodies; 0/Thyroid Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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