| Hypothesis: new concepts on the pathogenesis of early prosthetic valve endocarditis. | |
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MedLine Citation:
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PMID: 7144637 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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During the years 1970-1980, 697 patients had valve replacement surgery at our institution. Thirty patients subsequently developed prosthetic valve endocarditis (P.V.E.). Reexamination of the native valves of 25 of these patients revealed histopathological evidence of thromboendocarditis in 7, 5 of whom subsequently developed early P.V.E. In 3 out of 25 matched controls in whom P.V.E. was not diagnosed clinically, similar pathological findings were found; these patients all had fever pre- or post-operatively and were treated with a short antibacterial course, but no definite clinical diagnosis was made. We suggest that there is a close relationship between subclinical thromboendocarditis on the native valve and the early development of infective endocarditis on the implanted artificial valve. |
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Authors:
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E Leitersdorf; G Friedman; D Gozal; A Appelbaum; T Sacks; I Levij |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Medical hypotheses Volume: 9 ISSN: 0306-9877 ISO Abbreviation: Med. Hypotheses Publication Date: 1982 Sep |
Date Detail:
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Created Date: 1983-01-19 Completed Date: 1983-01-19 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7505668 Medline TA: Med Hypotheses Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 325-30 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Endocarditis, Bacterial
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pathology* Endocardium / pathology Heart Valve Prosthesis* Heart Valves / pathology Humans Postoperative Complications / pathology Thrombosis / pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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