Document Detail

Hypothesis: Correction of low vitamin D status among Arab women will prevent heart failure and improve cardiac function in established heart failure.
MedLine Citation:
PMID:  16828339     Owner:  NLM     Status:  MEDLINE    
Vitamin D deficiency is common in Arab countries particularly among women. This is the result of a low dietary intake of the vitamin, limited exposure to sunlight (a paradox in view of the high sunshine figures), skin colour, obesity and high parity. Apart from its adverse effects on bone in women and their offspring, vitamin D deficiency has the potential to cause or exacerbate heart failure through a number of mechanisms including activation of the renin-angiotensin system and increased arterial pressure. Accordingly, we propose that ensuring adequate vitamin D levels in Arab women will have a much greater impact on health than just the prevention of bone disease. In particular, we suggest that prevention and correction of vitamin D deficiency will reduce the incidence of heart failure and, for Arab women with established heart failure and vitamin D deficiency, improve cardiac function.
Hussein F Saadi; Elsadig Kazzam; Bahlul A Ghurbana; M Gary Nicholls
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Publication Detail:
Type:  Journal Article     Date:  2006-07-07
Journal Detail:
Title:  European journal of heart failure     Volume:  8     ISSN:  1388-9842     ISO Abbreviation:  Eur. J. Heart Fail.     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-10-30     Completed Date:  2007-01-30     Revised Date:  2011-06-08    
Medline Journal Info:
Nlm Unique ID:  100887595     Medline TA:  Eur J Heart Fail     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  694-6     Citation Subset:  IM    
Department of Internal Medicine, Faculty of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates.
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MeSH Terms
Arabs / statistics & numerical data*
Dietary Supplements
Heart Failure / ethnology,  etiology*,  prevention & control*
Nutritional Status
United Arab Emirates / epidemiology
Vitamin D / administration & dosage*
Vitamin D Deficiency / complications*,  epidemiology*,  ethnology
Women's Health
Reg. No./Substance:
1406-16-2/Vitamin D

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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