Document Detail

Hypothermia and rewarming induced by surface and He-O2 inhalate temperature control.
MedLine Citation:
PMID:  240798     Owner:  NLM     Status:  MEDLINE    
Hypothermia and rewarming were induced by a combination of temperature-controlled surface and inhalate methods in rabbits. To facilitate respiratory heat exchange, inhalate-respiratory tract temperature and humidity gradients and thermal conductivity were increased. In addition, the upper respiratory tract was bypassed by an endotracheal tube. To aid in maintaining satisfactory circulatory dynamics, hypercapnia and hypoxia were induced. The combined surface and inhalate method produced a markedly more effective rate of cooling than surface temperature-controlled method alone. Animals survived core temperatures as low as 20.9 degrees C with no complications. The noninvasive simplicity of this method suggests its potential applicability in many clinical situations.
A V Beran; K G Proctor; D R Sperling
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of applied physiology     Volume:  39     ISSN:  0021-8987     ISO Abbreviation:  J Appl Physiol     Publication Date:  1975 Aug 
Date Detail:
Created Date:  1975-12-28     Completed Date:  1975-12-28     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0376576     Medline TA:  J Appl Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  337-40     Citation Subset:  IM    
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MeSH Terms
Blood Gas Analysis
Blood Pressure
Heart Rate
Hemoglobins / analysis
Hydrogen-Ion Concentration
Hypothermia, Induced / methods*
Reg. No./Substance:
0/Hemoglobins; 7440-59-7/Helium; 7782-44-7/Oxygen

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