Document Detail


Hypothermia in the Setting of Experimental Acute Myocardial Infarction: A Comprehensive Review.
MedLine Citation:
PMID:  25271792     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A door-to-balloon time of less than 90 minutes is the gold standard for reperfusion therapy to treat acute myocardial infarction (MI). Because 30-day mortality remains ∼10%, new methods must be cultivated to limit myocardial injury. Therapeutic hypothermia has long been experimentally used to attenuate myocardial necrosis during MI with promising results, but the treatment has yet to gain popularity among most clinicians. Hypothermia, in the basic science setting, has been achieved using many techniques. In our review, we examine past and current methods of inducing hypothermia, benefits and setbacks of such methods, current and future clinical trials, and potential mechanisms.
Authors:
Michael J Herring; Sharon L Hale; Wangde Dai; Peyman Mesbah Oskui; Robert A Kloner
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-10-1
Journal Detail:
Title:  Therapeutic hypothermia and temperature management     Volume:  -     ISSN:  2153-7933     ISO Abbreviation:  Ther Hypothermia Temp Manag     Publication Date:  2014 Oct 
Date Detail:
Created Date:  2014-10-1     Completed Date:  -     Revised Date:  2014-10-2    
Medline Journal Info:
Nlm Unique ID:  101543518     Medline TA:  Ther Hypothermia Temp Manag     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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