| Hypothalamus Adult Neurogenesis in the Mammalian: Evidence, Functions, and Implications. | |
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MedLine Citation:
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PMID: 21495965 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Neurogenesis occurs in the adult brain in a constitutive manner under physiological circumstances within two regions: the dentate gyrus of the hippocampus and the subventricular zone of the lateral ventricles. In contrast to these two so-called neurogenic areas, other regions of the brain were considered to be primarily non-neurogenic in nature, implying that no new neurons were formed there under normal conditions. Recently, low proliferative activity was reported in the hypothalamus and the cell layers surrounding the third ventricle. This review summarizes recent evidence for adult neurogenesis in the hypothalamus, and points out the potential contributions of these new neurons to neural processing. We also discussed some technical considerations in investigating neurogenesis in the adult hypothalamus. It is believed that the hypothalamus could serve as a new source and target for stem cell transplantation. |
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Authors:
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Ti-Fei Yuan; Oscar Arias-Carrión |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-18 |
Journal Detail:
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Title: CNS & neurological disorders drug targets Volume: - ISSN: 1996-3181 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101269155 Medline TA: CNS Neurol Disord Drug Targets Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Experimental Neurology, Biomedical Research Center (BMFZ), Philipps University, Hans Meerwein, Str, D-35043 Marburg, Germany. arias@exp-neuro.de. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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