Document Detail


Hypothalamic neuropeptide systems as targets for potential anti-obesity drugs.
MedLine Citation:
PMID:  17266633     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Food intake and energy homeostasis are controlled by peripheral humoral signals, afferent neuronal pathways to the brain and central signals, represented, in particular, by neuropeptides. This review reports the status of development of novel compounds targeting some hypothalamic neuropeptide systems which are currently viewed as potential targets to treat obesity.
Authors:
E Dozio; M Ruscica; M Motta; P Magni
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Mini reviews in medicinal chemistry     Volume:  7     ISSN:  1389-5575     ISO Abbreviation:  Mini Rev Med Chem     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-02-01     Completed Date:  2007-03-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101094212     Medline TA:  Mini Rev Med Chem     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  11-9     Citation Subset:  IM    
Affiliation:
Istituto di Endocrinologia, Universita' degli Studi di Milano, via G. Balzaretti, 9, 20133 Milano-Italy.
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MeSH Terms
Descriptor/Qualifier:
Animals
Anti-Obesity Agents / pharmacology*
Humans
Hypothalamus / drug effects*,  metabolism
Neuropeptides / metabolism*
Chemical
Reg. No./Substance:
0/Anti-Obesity Agents; 0/Neuropeptides

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