Document Detail

Hypothalamic monoamines and their metabolites in the deermouse, Peromyscus maniculatus, during daily torpor.
MedLine Citation:
PMID:  2297395     Owner:  NLM     Status:  MEDLINE    
Deermice, subjected to food rationing, an ambient temperature below thermal neutrality and short photoperiod, were sacrificed in euthermia or during daily torpor. Hypothalamic monoamine and metabolite levels were quantified by HPLC with electrochemical detection. Significant elevations in the levels (pg/microgram protein) of dopamine, 3,4-dihydroxyphenylacetic acid, and homovanillic acid were noted in the torpid animals. The concentrations of norepinephrine and serotonin displayed no significant alterations between the euthermic and torpid states. However, the serotonin metabolite, 5-hydroxyindole-3-acetic acid, was elevated by almost 300%. These data suggest that an increase in activity of the hypothalamic serotonergic and dopaminergic systems occurs during daily torpor in the deermouse.
L H Lin; E B Pivorun
Related Documents :
9872595 - Lung lining fluid antioxidants in male broilers: age-related changes under thermoneutra...
3243865 - Group fractionation of free and conjugated steroids by means of disposable silica-based...
9053555 - Pre- and postnatal diagnosis of peroxisomal disorders using stable-isotope dilution gas...
9288865 - Errors in the selection of dialysate concentrates cause severe metabolic acidosis durin...
16726975 - Transitory acidification of semen as a potential method for the inactivation of some pa...
20004585 - Synthesis, anti-hiv and anti-oxidant activities of caffeoyl 5,6-anhydroquinic acid deri...
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of neural transmission. General section     Volume:  79     ISSN:  -     ISO Abbreviation:  J. Neural Transm. Gen. Sect.     Publication Date:  1990  
Date Detail:
Created Date:  1990-03-09     Completed Date:  1990-03-09     Revised Date:  2014-06-03    
Medline Journal Info:
Nlm Unique ID:  9002201     Medline TA:  J Neural Transm Gen Sect     Country:  AUSTRIA    
Other Details:
Languages:  eng     Pagination:  11-8     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
3,4-Dihydroxyphenylacetic Acid / metabolism
Body Temperature Regulation / physiology*
Circadian Rhythm
Dopamine / metabolism*,  physiology
Hibernation / physiology
Hypothalamus / metabolism,  physiology*
Norepinephrine / metabolism*,  physiology
Peromyscus / metabolism,  physiology*
Serotonin / metabolism*,  physiology
Grant Support
Reg. No./Substance:
102-32-9/3,4-Dihydroxyphenylacetic Acid; 333DO1RDJY/Serotonin; VTD58H1Z2X/Dopamine; X4W3ENH1CV/Norepinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Different laws govern motor activity in sleep than in wakefulness.
Next Document:  Semistarvation-induced hyperactivity compensates for decreased norepinephrine and dopamine turnover ...