| Hypothalamic-hypophyseal dysgenesis as a neuroimaging correlate of pituitary hormone deficiency in anophthalmia. | |
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MedLine Citation:
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PMID: 8909226 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To document the association of neurohypophyseal dysgenesis with hypopituitarism in a child with primary bilateral anophthalmia. METHODS: An infant with bilateral anophthalmia underwent magnetic resonance imaging and endocrinologic evaluation. RESULTS: Magnetic resonance imaging showed dysgenesis confined to the hypothalamus and hypophyseal stalk. Endocrinologic testing showed low serum cortisol and pituitary gonadotropin levels. CONCLUSION: Magnetic resonance imaging can help predict which children with anophthalmia will have endocrinologic deficiencies. |
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Authors:
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M C Brodsky; J P Frindik |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of ophthalmology Volume: 122 ISSN: 0002-9394 ISO Abbreviation: Am. J. Ophthalmol. Publication Date: 1996 Nov |
Date Detail:
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Created Date: 1996-11-27 Completed Date: 1996-11-27 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370500 Medline TA: Am J Ophthalmol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 747-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Ophthalmology, University of Arkansas for Medical Sciences, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abnormalities, Multiple
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blood,
genetics* Anophthalmos / blood, genetics* Gonadotropins, Pituitary / blood, deficiency Humans Hydrocortisone / blood, deficiency Hypopituitarism / blood, diagnosis*, genetics Hypothalamo-Hypophyseal System / abnormalities*, pathology* Infant, Newborn Magnetic Resonance Imaging Male Pituitary Hormones / blood, deficiency* |
| Chemical | |
Reg. No./Substance:
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0/Gonadotropins, Pituitary; 0/Pituitary Hormones; 50-23-7/Hydrocortisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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