Document Detail

Hypothalamic hamartoma, precocious puberty and gelastic seizures: a special model of "epileptic" developmental disorder.
MedLine Citation:
PMID:  10937169     Owner:  NLM     Status:  MEDLINE    
Based on a review of the literature and a detailed longitudinal single case study of a child with early onset gelastic seizures and hypothalamic hamartoma, the authors review the arguments suggesting that the acquired cognitive and behavioral symptoms seen in the majority of cases of this special epileptic syndrome result from a direct effect of the seizures. The early neurobehavioral profile of the case presented in this paper and that of a previous study is particular and combines features of a pervasive developmental and an attention deficit disorder which are probably closely related to the particular location of the epilepsy and its spread from the hypothalamus.
T Deonna; A L Ziegler
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Epileptic disorders : international epilepsy journal with videotape     Volume:  2     ISSN:  1294-9361     ISO Abbreviation:  Epileptic Disord     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-08-29     Completed Date:  2000-08-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100891853     Medline TA:  Epileptic Disord     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  33-7     Citation Subset:  IM    
Pediatric Department, CHUV, Lausanne, Switzerland.
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MeSH Terms
Behavior / physiology
Child, Preschool
Cognition Disorders / etiology,  psychology
Epilepsy / pathology*,  psychology
Hamartoma / complications*,  psychology
Hypothalamic Diseases / complications*,  psychology
Longitudinal Studies
Magnetic Resonance Imaging
Puberty, Precocious / complications*,  psychology
Seizures / complications*,  psychology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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