Document Detail


Hypotensive brain stem necrosis or cardiac arrest encephalopathy?
MedLine Citation:
PMID:  7376826     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Selective symmetrical necroses of many tegmental brain stem nuclei including motor cranial nerve nuclei, superior and inferior colliculi, cuneate and gracilis nuclei, and others are known as hypotensive brain stem necrosis (Gilles 1969). We found such lesions in eight infants and seven adults. Examination of their clinical records revealed a well documented episode of cardiac arrest in each case. Cardiac output was restored in all but one patient 5 min to 4 h after the beginning of resuscitation. All patients remained comatose in a decerebrate state up to their death 17 h to 4 weeks after admission. Our findings and a review of the literature indicate that this type of lesion relates specifically to cardiac arrest. The term "hypotensive brain stem necrosis"is a misnomer and should be replaced by the term "cardiac arrest encephalopathy".
Authors:
R C Janzer; R L Friede
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neuropathologica     Volume:  50     ISSN:  0001-6322     ISO Abbreviation:  Acta Neuropathol.     Publication Date:  1980  
Date Detail:
Created Date:  1980-07-28     Completed Date:  1980-07-28     Revised Date:  2007-11-09    
Medline Journal Info:
Nlm Unique ID:  0412041     Medline TA:  Acta Neuropathol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  53-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Brain Stem / pathology*
Cardiac Output
Child
Child, Preschool
Decerebrate State / pathology
Female
Heart Arrest / pathology*
Humans
Hypotension / pathology*
Infant
Infant, Newborn
Male
Middle Aged
Necrosis
Resuscitation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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