Document Detail


Hypotension and bradycardia in infants after the use of topical brimonidine and beta-blockers.
MedLine Citation:
PMID:  12690374     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Brimonidine is a selective alpha-2 adrenergic agonist used to treat glaucoma. There have been several reports of central nervous system depression after its use in infants. We observed rapid-onset bradycardia and decreased blood pressure in addition to central nervous system depression in 2 infants who received concomitant topical brimonidine and beta-blockers.
Authors:
Nils K Mungan; Thomas W Wilson; Ken K Nischal; Gideon Koren; Alex V Levin
Related Documents :
3876024 - Ventilatory pattern following diphtheria-tetanus-pertussis immunization in infants at r...
3283314 - Renal failure in sick hypertensive premature infants receiving captopril therapy.
1128984 - Treatment of severe apnea in prematures with orally administered theophylline.
20172814 - Attractor structure discriminates sleep states: recurrence plot analysis applied to inf...
17177684 - Molecular fingerprinting of the intestinal microbiota of infants in whom atopic eczema ...
24731484 - Early hyperglycemia is associated with poor gross motor outcome in asphyxiated term new...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus     Volume:  7     ISSN:  1091-8531     ISO Abbreviation:  J AAPOS     Publication Date:  2003 Feb 
Date Detail:
Created Date:  2003-04-11     Completed Date:  2003-10-29     Revised Date:  2006-04-21    
Medline Journal Info:
Nlm Unique ID:  9710011     Medline TA:  J AAPOS     Country:  United States    
Other Details:
Languages:  eng     Pagination:  69-70     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, The Hospital for Sick Children, University of Toronto, Ontario, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Administration, Topical
Adrenergic alpha-Agonists / administration & dosage*,  adverse effects*
Adrenergic beta-Antagonists / administration & dosage*,  adverse effects*
Bradycardia / chemically induced*
Female
Glaucoma / drug therapy*,  physiopathology
Humans
Hypotension / chemically induced*
Infant
Infant, Newborn
Intraocular Pressure / drug effects
Quinoxalines / administration & dosage*,  adverse effects*
Chemical
Reg. No./Substance:
0/Adrenergic alpha-Agonists; 0/Adrenergic beta-Antagonists; 0/Quinoxalines; 59803-98-4/brimonidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Intensity and complexity index of disease for strabismus surgery.
Next Document:  Pseudotumor cerebri in idiopathic aplastic anemia.