| Hypotension at presentation is an indicator of poor prognosis in acute intracerebral haemorrhage. | |
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MedLine Citation:
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PMID: 18988405 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To identify frequency of hypotension in a large cohort of patients with intracerebral haemorrhage and its prognostic significance. METHODS: We retrospectively reviewed medical records of 920 patients with spontaneous intracerebral haemorrhage (ICH). Patients were divided in three groups based on Diastolic blood pressure (DBP); hypotensive group (DBP < 70 mmHg), normotensive group (DBP; 71-90 mmHg) and hypertensive group (DBP > 90 mmHg). RESULTS: Of the total patients with ICH, 7% (64) presented with hypotension, 13% (120) were normotensive and 80% (736) were hypertensive. In the hypotensive group, 37% (24) patients died as compared to 25%(30) in normotensive group and 25% (182) in hypertensive group (p = 0.03). Hypotension at presentation, thalamic and lobar haemorrhages were predictors of poor outcome. Patients with diastolic BP of less than 70 were significantly more likely to die than with DBP 71-90 (OR = 1.9, 95% CI; 1.1-2.9, p = 0.03). This relationship was still significant after adjusting for age, sex, history of presentation, coma at presentation and location of haemorrhage (OR = 1.45, 95% CI; 1.0-2.2, p = 0.045). CONCLUSION: Our findings suggest that hypotension at presentation is a predictor of poor outcome in patients with ICH. Patients with diastolic blood pressure less than 70 are more likely to have a fatal outcome as compared to those with normal blood pressure. |
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Authors:
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Mohammad Wasay; Bhojo A Khealani; Saad Shafqat; Ayesha Kamal; Nadir Ali Syed |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: JPMA. The Journal of the Pakistan Medical Association Volume: 58 ISSN: 0030-9982 ISO Abbreviation: J Pak Med Assoc Publication Date: 2008 Jul |
Date Detail:
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Created Date: 2008-11-07 Completed Date: 2008-12-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7501162 Medline TA: J Pak Med Assoc Country: Pakistan |
Other Details:
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Languages: eng Pagination: 359-61 Citation Subset: IM |
Affiliation:
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Department of Neurology and Community Heath Sciences, The Aga Khan University, Karachi. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Cerebral Hemorrhage / complications, diagnosis, mortality* Female Humans Hypotension / epidemiology* Logistic Models Male Middle Aged Pakistan / epidemiology Prognosis Retrospective Studies Risk Factors |
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