Document Detail

Hyposplenism and disseminated intravascular coagulation (DIC) in fulminant pneumococcal sepsis.
MedLine Citation:
PMID:  887988     Owner:  NLM     Status:  MEDLINE    
A case of pneumococcal sepsis with DIC is reported. The patient had hyposplenism from thorium dioxide administration 23 years previously. Evidences of consumptive coagulopathy were verified by clinical manifestations of shock, generalized petechiae, abnormal hemostatic studies, and autopsy findings. The possible pathogenetic mechanism(s) of DIC in hyposplenism and pneumococcemia are reviewed.
P Gerjarusak; D R Hinthorn; C Liu
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  70     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  1977 Aug 
Date Detail:
Created Date:  1977-09-29     Completed Date:  1977-09-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  995-7     Citation Subset:  AIM; IM    
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MeSH Terms
Disseminated Intravascular Coagulation / diagnosis,  etiology*,  microbiology
Pneumococcal Infections*
Sepsis / complications*,  microbiology
Splenic Diseases / chemically induced,  complications*,  microbiology
Thorium Dioxide / adverse effects
Reg. No./Substance:
1314-20-1/Thorium Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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