| Hyposensitization therapy of Parietaria-sensitive patients with a tyrosine adsorbed allergoid, Pollinex Parietaria (Bencard Parietaria). | |
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MedLine Citation:
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PMID: 1669563 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirty patients suffering from allergy to Parietaria pollen were treated with either a new tyrosine-adsorbed allergoid of Parietaria judaica pollen (Pollinex Parietaria) or a commercially available alum-adsorbed extract (Alavac) as control. A reduced response to nasal provocation was seen in 7 out of 11 patients following treatment with Pollinex and 1 out of 10 after control treatment. 9 out of 11 and 3 out of 10, respectively, showed reduced skin test activity. Patients who received Pollinex tended to have fewer nasal symptoms during the pollen season. Pollinex induced larger increases in P. judaica-specific IgG antibody than did the control product. Side effects of therapy were similar between the two groups of patients. Pollinex Parietaria thus shows good potential for the control of allergy to Parietaria pollen. |
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Authors:
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F Bonifazi; L Antonicelli; M B Bilò; S Pucci; I H Taylor; A W Wheeler; L J Youlten |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Journal of investigational allergology & clinical immunology : official organ of the International Association of Asthmology (INTERASMA) and Sociedad Latinoamericana de Alergia e Inmunología Volume: 1 ISSN: 1018-9068 ISO Abbreviation: J Investig Allergol Clin Immunol Publication Date: 1991 Feb |
Date Detail:
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Created Date: 1994-02-22 Completed Date: 1994-02-22 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9107858 Medline TA: J Investig Allergol Clin Immunol Country: SPAIN |
Other Details:
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Languages: eng Pagination: 37-44 Citation Subset: IM |
Affiliation:
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Servizio Allergologia Respiratoria, Ospedale Generale Umberto I, Ancona, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Allergens / administration & dosage*, immunology, isolation & purification Desensitization, Immunologic / adverse effects, methods* Drug Combinations Female Glutaral / administration & dosage, immunology Humans Immunoglobulin G / blood Immunosorbent Techniques Male Middle Aged Plant Extracts / administration & dosage, immunology Plant Proteins / administration & dosage, immunology Pollen / immunology* Rhinitis, Allergic, Seasonal / immunology, therapy* Tyrosine / administration & dosage, immunology |
| Chemical | |
Reg. No./Substance:
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0/Allergens; 0/Allergoid; 0/Drug Combinations; 0/Immunoglobulin G; 0/Par j I protein, Parietaria judaica; 0/Plant Extracts; 0/Plant Proteins; 111-30-8/Glutaral; 55520-40-6/Tyrosine; 56996-84-0/Pollinex |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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