Document Detail

Hyporeninemic hypoaldosteronism in infancy.
MedLine Citation:
PMID:  6353255     Owner:  NLM     Status:  MEDLINE    
Hyporeninemic hypoaldosteronism was observed in an infant at the age of 3 months. Persistent hyperkalemia, hyperchloremic acidosis and salt wasting were present. All abnormal electrolyte values were corrected by the administration of fludrocortisone. Both active and inactive renin were lowered. This infant had also an unexplained spastic quadriplegia and psychomotor retardation. Hyporeninemic hypoaldosteronism should be considered to be one of the causes of salt-losing in infancy.
L Monnens; T Fiselier; B Bos; P van Munster
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nephron     Volume:  35     ISSN:  0028-2766     ISO Abbreviation:  Nephron     Publication Date:  1983  
Date Detail:
Created Date:  1983-11-23     Completed Date:  1983-11-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0331777     Medline TA:  Nephron     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  140-2     Citation Subset:  IM    
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MeSH Terms
Acidosis / blood
Aldosterone / deficiency*
Chlorides / blood
Fludrocortisone / therapeutic use
Potassium / blood
Psychomotor Disorders / etiology
Quadriplegia / etiology
Renin / blood*
Sodium / metabolism
Reg. No./Substance:
0/Chlorides; 127-31-1/Fludrocortisone; 52-39-1/Aldosterone; 7440-09-7/Potassium; 7440-23-5/Sodium; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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