Document Detail


Hypopituitarism masquerading as Prasad's syndrome: a case report.
MedLine Citation:
PMID:  22389997     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Prasad's syndrome is characterized by geophagia, growth retardation, hypogonadism, and zinc deficiency. We report a 15-year-old boy whose medical history and clinical and laboratory findings were fully compatible with Prasad's syndrome. In addition to severe growth retardation and pubertal delay, iron deficiency anemia and zinc deficiency were determined. His gliadin and endomysium antibodies were negative. The thyroid hormone levels were in normal range but basal gonadotropins and testosterone levels were low for his age. Detailed endocrinological evaluation revealed growth hormone deficiency and hypogonadotropic hypogonadism. Pituitary gland magnetic resonance imaging revealed pituitary hypoplasia. In our opinion, before the diagnosis of Prasad's syndrome, endocrine evaluation should be done in these patients and hypopituitarism should be ruled out. Hypogonadotropic hypogonadism and growth hormone deficiency may be masked by Prasad's syndrome.
Authors:
Fatma Demirel; Tekin Aksu; Ihsan Esen; Neşe Yarali; Gülhan Karakaya; Bahattin Tunç
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Turkish journal of pediatrics     Volume:  53     ISSN:  0041-4301     ISO Abbreviation:  Turk. J. Pediatr.     Publication Date:    2011 Nov-Dec
Date Detail:
Created Date:  2012-03-06     Completed Date:  2012-03-22     Revised Date:  2012-10-25    
Medline Journal Info:
Nlm Unique ID:  0417505     Medline TA:  Turk J Pediatr     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  702-4     Citation Subset:  IM    
Affiliation:
Department of Pediatric Endocrinology, Ankara Children's Hematology and Oncology Training Hospital, Ankara, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Anemia, Iron-Deficiency / diagnosis*
Diagnosis, Differential
Growth Disorders / diagnosis*
Humans
Hypopituitarism / diagnosis*
Male
Puberty, Delayed / diagnosis*
Syndrome
Comments/Corrections
Comment In:
Turk J Pediatr. 2012 May-Jun;54(3):321; author reply 322   [PMID:  23094550 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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