Document Detail

Hypopituitarism due to Hydrocephalus: Case Report and Review of the Literature.
MedLine Citation:
PMID:  22573017     Owner:  NLM     Status:  In-Data-Review    
Introduction: Although rare, chronic hydrocephalus may cause amenorrhea and delayed puberty associated with obesity as the main endocrine manifestations. Since the first operation carried out in 1950 on a patient with amenorrhea and hydrocephalus, fewer than 30 patients with these features have been reported. Case Report: Our patient represents a teenage case of primary amenorrhea, partial adrenal insufficiency and adult growth hormone deficiency caused by hydrocephalus due to aqueductal stenosis. Our English-language literature search for similar well-documented cases yielded less than 30 cases. Our management consisted of endoscopic third ventriculostomy, which resulted in regular menstrual cycles and normalization of somato- and adrenocorticotropic axes. Discussion: This is a rare case of a 20-year-old woman with primary amenorrhea caused by hydrocephalus due to aqueductal stenosis. Neurosurgical treatment produced relief in hypothalamic hydrodynamics tension, allowing recovery of hormonal function and restoring normal menstrual cycles.
Fernando Campos Gomes Pinto; Malebranche Berardo Carneiro da Cunha Neto; Manuela Giuliani Marcondes Rocha; Daniel Vicaria do Lago; Marcello Delano Bronstein; Manoel Jacobsen Teixeira
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Publication Detail:
Type:  Journal Article     Date:  2012-05-03
Journal Detail:
Title:  Pediatric neurosurgery     Volume:  47     ISSN:  1423-0305     ISO Abbreviation:  Pediatr Neurosurg     Publication Date:  2011  
Date Detail:
Created Date:  2012-05-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114967     Medline TA:  Pediatr Neurosurg     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  303-6     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 S. Karger AG, Basel.
Neuroendocrine Unit, Institute of Psychiatry, São Paulo, Brazil.
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