Document Detail

Hypophosphatemic oncogenic osteomalacia: report of three new cases.
MedLine Citation:
PMID:  3217995     Owner:  NLM     Status:  MEDLINE    
Three cases of connective tissue tumors causing hypophosphatemic osteomalacia are reported and the literature is reviewed. In two of our patients the tumors were completely excised with total disappearance of the symptoms. In one case a total excision was not possible and the symptoms of this patient have not completely disappeared. The substance responsible for the syndrome has not been identified yet, but probably interferes with vitamin D renal hydroxylation, thus causing osteomalacia. As more than 30 per cent of cases of this condition have been reported in the last 5 years, it is suggested that these tumors are more frequent than previously believed.
M Papotti; M P Foschini; G Isaia; G Rizzi; C M Betts; V Eusebi
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Tumori     Volume:  74     ISSN:  0300-8916     ISO Abbreviation:  Tumori     Publication Date:  1988 Oct 
Date Detail:
Created Date:  1989-03-06     Completed Date:  1989-03-06     Revised Date:  2008-12-12    
Medline Journal Info:
Nlm Unique ID:  0111356     Medline TA:  Tumori     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  599-607     Citation Subset:  IM    
Dipartimento di Scienze Biomediche e Oncologia Umana, Università di Torino, Italia.
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MeSH Terms
Middle Aged
Neoplasms, Connective Tissue / blood,  complications,  pathology*
Osteomalacia / blood,  etiology,  pathology*
Phosphates / blood*
Reg. No./Substance:

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