Document Detail

Hyponatremic seizure in a child using desmopressin for nocturnal enuresis.
MedLine Citation:
PMID:  9529469     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Intranasal desmopressin has been used extensively to treat primary nocturnal enuresis. While it has proven to be a safe, effective agent for many who are affected by this condition, the potential for complications exists. OBJECTIVES: To report a case of severe hyponatremia associated with a generalized tonic-clonic seizure in a 10-year-old boy who had been receiving intranasal desmopressin nightly for nocturnal enuresis and to briefly review therapeutic options for nocturnal enuresis; and to present the role of desmopressin. SETTING: Georgetown University Medical Center, Washington, DC. INTERVENTION: Fluid restriction and intravenous isotonic saline solution with 5% dextrose was administered to raise the serum sodium level. OUTCOME: Prevention of further seizures with normalization of serum sodium levels without any obvious neurological sequelae. CONCLUSIONS: This case illustrates the importance of weighing the benefits and risks of intranasal desmopressin therapy.
M B Donoghue; M E Latimer; H L Pillsbury; J H Hertzog
Related Documents :
1052259 - Psychiatry on the prevention of crime.
16511649 - Epileptic nystagmus: two case reports, clinical and pathophysiological review of the li...
19694799 - Migralepsy: a call for a revision of the definition.
9034419 - Seizure resulting from a venlafaxine overdose.
9253489 - Perioral myoclonia with absences? a case report with eeg and voltage mapping analysis.
3939749 - Pathologic myoclonus of the newborn: electrographic and clinical correlations.
22307189 - Posttraumatic pulmonary pseudocysts as a manifestation of child abuse.
24615649 - Adult-onset laryngomalacia: case reports and review of management.
2802459 - External and middle ear malformations: autosomal dominant genetic transmission.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of pediatrics & adolescent medicine     Volume:  152     ISSN:  1072-4710     ISO Abbreviation:  Arch Pediatr Adolesc Med     Publication Date:  1998 Mar 
Date Detail:
Created Date:  1998-04-16     Completed Date:  1998-04-16     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  9422751     Medline TA:  Arch Pediatr Adolesc Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  290-2     Citation Subset:  AIM; IM    
Department of Pediatrics, Georgetown University Medical Center, Washington, DC, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Deamino Arginine Vasopressin / adverse effects*,  therapeutic use
Enuresis / drug therapy*
Epilepsy, Tonic-Clonic / etiology*
Hyponatremia / chemically induced*,  complications
Renal Agents / adverse effects*,  therapeutic use
Reg. No./Substance:
0/Renal Agents; 16679-58-6/Deamino Arginine Vasopressin
Comment In:
Arch Pediatr Adolesc Med. 1998 Oct;152(10):1037-8   [PMID:  9790620 ]
Arch Pediatr Adolesc Med. 1998 Sep;152(9):930-1   [PMID:  9743047 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Vaccine-associated liability risk and provider immunization practices.
Next Document:  Clinical teaching rounds. A case-oriented faculty development program.