Document Detail

Hyponatremia in pulmonary TB: evidence of ectopic antidiuretic hormone production.
MedLine Citation:
PMID:  20051406     Owner:  NLM     Status:  MEDLINE    
Hyponatremia is among the most common biochemical abnormalities in hospital inpatients. The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is one of several causes of hyponatremia, particularly in patients with pulmonary diseases. The mechanism of SIADH associated with pulmonary infection is, however, poorly understood. We report an unusual case of hyponatremia in a man with pulmonary TB and central diabetes insipidus with biochemical evidence of ectopic antidiuretic hormone production as a possible mechanism causing hyponatremia.
Paul Lee; Ken K Y Ho
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Chest     Volume:  137     ISSN:  1931-3543     ISO Abbreviation:  Chest     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-01-06     Completed Date:  2010-02-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  United States    
Other Details:
Languages:  eng     Pagination:  207-8     Citation Subset:  AIM; IM    
Department of Endocrinology, St Vincent's ospital and Pituitary Research Unit, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, Sydney, New South Wales, Australia.
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MeSH Terms
Antidiuretic Agents / therapeutic use
Deamino Arginine Vasopressin / therapeutic use
Follow-Up Studies
Hyponatremia / drug therapy,  etiology*,  metabolism
Middle Aged
Sodium / blood,  urine
Tuberculosis, Pulmonary / blood,  complications*
Vasopressins / biosynthesis*,  blood
Reg. No./Substance:
0/Antidiuretic Agents; 11000-17-2/Vasopressins; 16679-58-6/Deamino Arginine Vasopressin; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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