Document Detail

Hyponatremia associated with sertraline and fluoxetine: a case report.
MedLine Citation:
PMID:  11965835     Owner:  NLM     Status:  MEDLINE    
The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a rare but serious adverse effect of the selective serotonin reuptake inhibitors (SSRIs). Although many case reports describe this association, few report the effect of rechallenge with another SSRI. We present a case of an elderly patient who developed hyponatremia with sertraline and SIADH when rechallenged with fluoxetine.
Kalani Raphael; Jinichi Tokeshi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Hawaii medical journal     Volume:  61     ISSN:  0017-8594     ISO Abbreviation:  Hawaii Med J     Publication Date:  2002 Mar 
Date Detail:
Created Date:  2002-04-22     Completed Date:  2002-05-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2984209R     Medline TA:  Hawaii Med J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  46-7     Citation Subset:  IM    
University of Hawaii, John A. Burns School of Medicine, USA.
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MeSH Terms
Aged, 80 and over
Antidepressive Agents / adverse effects*
Antidepressive Agents, Second-Generation / adverse effects
Depressive Disorder / drug therapy
Fluoxetine / adverse effects*
Hyponatremia / etiology*,  therapy
Inappropriate ADH Syndrome / etiology*,  therapy
Serotonin Uptake Inhibitors / adverse effects*
Sertraline / adverse effects*
Treatment Outcome
Reg. No./Substance:
0/Antidepressive Agents; 0/Antidepressive Agents, Second-Generation; 0/Serotonin Uptake Inhibitors; 54910-89-3/Fluoxetine; 79617-96-2/Sertraline

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