| Hypomagnesemia resulting from adrenaline infusion in ewes: its relation to lipolysis. | |
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MedLine Citation:
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PMID: 892696 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Intravenous infusion of adrenaline (40 microgram Kg-1 h-1 for 5 hrs) causes hypomagnesemia in ewes. Hypomagnesemia is increased by phentolamine and inhibited by propranolol. Thyroidectomy, with thyroxine supplementation, does not inhibit the hypomagnesemia caused by adrenaline and phentolamine. Sodium nicotinate (15 mg Kg-1 h-1 for 5 hrs) inhibits the increase in non-esterified fatty acids and hypomagnesemia resulting from infusion of adrenaline and phentolamine. Sodium nicotinate inhibits the increase in non-esterified fatty acids and hypomagnesemia resulting from theophylline infusion (20 mg Kg-1 h-1 for 90 min). It is concluded that an increase in the level of intra-cellular cyclic AMP due to beta adrenergic stimulation by adrenaline or to inhibition of phosphodiesterases by theophylline, results in hypomagnesemia which seems to be correlated with stimulation of lipolysis. |
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Authors:
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Y Rayssiguier |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme Volume: 9 ISSN: 0018-5043 ISO Abbreviation: Horm. Metab. Res. Publication Date: 1977 Jul |
Date Detail:
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Created Date: 1977-10-14 Completed Date: 1977-10-14 Revised Date: 2009-02-19 |
Medline Journal Info:
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Nlm Unique ID: 0177722 Medline TA: Horm Metab Res Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 309-14 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Epinephrine / pharmacology* Fatty Acids, Nonesterified / blood* Female Magnesium / blood* Nicotinic Acids / pharmacology Phentolamine / pharmacology Propranolol / pharmacology Sheep Theophylline / pharmacology Thyroidectomy Thyroxine / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids, Nonesterified; 0/Nicotinic Acids; 50-60-2/Phentolamine; 51-43-4/Epinephrine; 525-66-6/Propranolol; 58-55-9/Theophylline; 7439-95-4/Magnesium; 7488-70-2/Thyroxine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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