Document Detail


Hypolipidemic activity of seeds of Cassia tora Linn.
MedLine Citation:
PMID:  15013188     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ethanolic extract of seeds of Cassia tora L. and its fractions were investigated for hypolipidemic activity on triton induced hyperlipidemic profile. Ethanolic extract and its ether soluble and water soluble fraction decreased serum level of total cholesterol by 42.07, 40.77 and 71.25%, respectively. On the other hand ethanolic extract, ether soluble fraction and water soluble fraction increased the serum HDL-cholesterol level by 6.72, 17.20 and 19.18%, respectively. Ethanolic extract, ether fraction and water fraction decreased triglyceride level by 26.84, 35.74 and 38.46%, respectively. The reduction in LDL-cholesterol level by ethanolic extract, ether soluble fraction and water soluble fraction were 69.25, 72.06 and 76.12%, respectively.
Authors:
Umesh K Patil; S Saraf; V K Dixit
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of ethnopharmacology     Volume:  90     ISSN:  0378-8741     ISO Abbreviation:  J Ethnopharmacol     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-03-11     Completed Date:  2004-04-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7903310     Medline TA:  J Ethnopharmacol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  249-52     Citation Subset:  IM    
Affiliation:
Department of Pharmaceutical Sciences, Dr Hari Singh Gour University, Sagar 470003, MP, India.
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MeSH Terms
Descriptor/Qualifier:
Animals
Antilipemic Agents / isolation & purification,  therapeutic use*
Cassia* / chemistry
Female
Hyperlipidemias / blood,  chemically induced,  drug therapy*
Male
Phytotherapy / methods
Plant Extracts / isolation & purification,  therapeutic use
Polyethylene Glycols / toxicity
Rats
Rats, Wistar
Seeds / chemistry
Chemical
Reg. No./Substance:
0/Antilipemic Agents; 0/Plant Extracts; 0/Polyethylene Glycols; 25301-02-4/tyloxapol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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