| Hypolipidemic effect of bamboo shoot oil (P. pubescens) in Sprague-Dawley rats. | |
| | |
MedLine Citation:
|
PMID: 20722933 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Atherosclerosis and its related complications are the leading causes of death in the West and in many developed countries. This study aims to investigate the hypolipidemic effect of bamboo shoot oil (BSO) in Sprague-Dawley rats. A group of rats had induced hyperlipidemia, hypercholesterolemia, and fatty liver by being fed with a high-fat, high-cholesterol diet for 4 wk. The control group was administered 10 mL distilled water per kg body weight, while the other groups were, respectively, administered 250 mg beta-sitosterol, 250 mg BSO, 500 mg BSO, and 1000 mg BSO per kg body weight by oral gavage. The results demonstrated that BSO could significantly decrease the levels of total cholesterol, triacylglycerol, low-density lipoprotein-cholesterol, phytosterol, lipoprotein lipase, hepatic lipase, and atherogenic index in serum, and increase the levels of cholesterol in feces. It could also significantly decrease the level of relative liver weight and liver lipids. The pronounced hypolipidemic effects of BSO might be attributed to its ability to inhibit cholesterol absorption and increase cholesterol excretion. These results suggest that consuming BSO may provide benefits in managing hypercholesterolemia. Therefore, BSO may be a good candidate for development as a functional food and nutraceutical. |
| | |
Authors:
|
Baiyi Lu; Daozhong Xia; Weisu Huang; Xiaoqin Wu; Ying Zhang; Yiyuan Yao |
Related Documents
:
|
5637433 - Transfer of locally synthesized cholesterol from intestinal wall to intestinal lymph. 5641613 - Effects of diet on hepatic triglyceride synthesis. 22286913 - Evidence-based guideline of the german nutrition society: carbohydrate intake and preve... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of food science Volume: 75 ISSN: 1750-3841 ISO Abbreviation: J. Food Sci. Publication Date: 2010 Aug |
Date Detail:
|
Created Date: 2010-08-20 Completed Date: 2011-01-18 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0014052 Medline TA: J Food Sci Country: United States |
Other Details:
|
Languages: eng Pagination: H205-11 Citation Subset: IM |
Affiliation:
|
Dept. of Food Science and Nutrition, Zhejiang Univ., Hangzhou, China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Cholesterol / analysis, blood, metabolism Diet, Atherogenic Dose-Response Relationship, Drug Fatty Liver / pathology Feces / chemistry Hyperlipidemias / blood, drug therapy, pathology, prevention & control* Hypolipidemic Agents / therapeutic use* Lipids / analysis, blood, chemistry Liver / chemistry, pathology Male Organ Size / drug effects Phytosterols / analysis, blood, chemistry Phytotherapy* Plant Oils / chemistry, therapeutic use* Plant Shoots / chemistry* Poaceae / chemistry* Random Allocation Rats Rats, Sprague-Dawley |
| Chemical | |
Reg. No./Substance:
|
0/Hypolipidemic Agents; 0/Lipids; 0/Phytosterols; 0/Plant Oils; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effects of vitamin D3 on expression of tumor necrosis factor-alpha and chemokines by monocytes.
Next Document: Detection of E. coli O157:H7 from ground beef using Fourier transform infrared (FT-IR) spectroscopy ...