Document Detail


Hypolipidemic Activity of Eryngium carlinae on Streptozotocin-Induced Diabetic Rats.
MedLine Citation:
PMID:  22162811     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Diabetes mellitus (DM) is a significant risk factor for the development of cardiovascular complications. This study was undertaken to investigate the effect of chronic administration of ethanolic extract of Eryngium carlinae on glucose, creatinine, uric acid, total cholesterol, and triglycerides levels in serum of streptozotocin- (STZ-) induced diabetic rats. Triglycerides, total cholesterol, and uric acid levels increased in serum from diabetic rats. The treatment with E. carlinae prevented these changes. The administration of E. carlinae extract reduced the levels of creatinine, uric acid, total cholesterol, and triglycerides. Thus administration of E. carlinae is able to reduce hyperlipidemia related to the cardiovascular risk in diabetes mellitus.
Authors:
Ruth Noriega-Cisneros; Omar Ortiz-Ávila; Edgar Esquivel-Gutiérrez; Mónica Clemente-Guerrero; Salvador Manzo-Avalos; Rafael Salgado-Garciglia; Christian Cortés-Rojo; Istvan Boldogh; Alfredo Saavedra-Molina
Publication Detail:
Type:  Journal Article     Date:  2011-11-24
Journal Detail:
Title:  Biochemistry research international     Volume:  2012     ISSN:  2090-2255     ISO Abbreviation:  Biochem Res Int     Publication Date:  2012  
Date Detail:
Created Date:  2011-12-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101546751     Medline TA:  Biochem Res Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  603501     Citation Subset:  -    
Affiliation:
Instituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, 58030 Morelia, Michoacán, Mexico.
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