| Hypolipemic effect of water extracts of Picrorrhiza kurroa in high fat diet treated mouse. | |
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MedLine Citation:
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PMID: 17056204 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A hypolipemic effect of the water extract of Picrorrhiza kurroa (PR) was observed in a high fat diet feeding hyperlipemic mouse at doses of 50, 100 and 200 mg/kg, orally, once a day for 12 weeks. Liver weight, serum aspartate transferase (AST), alanine transferase (ALT), low density lipoprotein (LDL), triglyceride and total cholesterol levels were significantly reduced by the treatment. On the contrary, serum HDL level seems not affected by P. kurroa water extract. |
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Authors:
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Hyeung Sik Lee; Choon Bo Yoo; Sae Kwang Ku |
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Publication Detail:
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Type: Journal Article Date: 2006-09-22 |
Journal Detail:
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Title: Fitoterapia Volume: 77 ISSN: 0367-326X ISO Abbreviation: Fitoterapia Publication Date: 2006 Dec |
Date Detail:
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Created Date: 2006-11-20 Completed Date: 2007-02-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 16930290R Medline TA: Fitoterapia Country: Netherlands |
Other Details:
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Languages: eng Pagination: 579-84 Citation Subset: IM |
Affiliation:
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Department of Herbal Biotechnology, Daegu Haany University, Gyeongsan, 712-715, Republic of Korea. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Alanine Transaminase / blood Animals Antilipemic Agents / administration & dosage, pharmacology*, therapeutic use Aspartate Aminotransferases / blood Cholesterol / blood Cholesterol, LDL / blood Dietary Fats / administration & dosage Disease Models, Animal Dose-Response Relationship, Drug Liver / drug effects*, enzymology Male Mice Mice, Inbred ICR Obesity / drug therapy* Phytotherapy* Picrorhiza* Plant Extracts / administration & dosage, pharmacology*, therapeutic use Plant Roots Plant Stems Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Antilipemic Agents; 0/Cholesterol, LDL; 0/Dietary Fats; 0/Plant Extracts; 0/Triglycerides; 57-88-5/Cholesterol; EC 2.6.1.1/Aspartate Aminotransferases; EC 2.6.1.2/Alanine Transaminase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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