Document Detail

Hypoglycemia with a large retroperitoneal mass - Case report.
MedLine Citation:
PMID:  25437682     Owner:  NLM     Status:  Publisher    
INTRODUCTION: Retroperitoneal sarcomas have rarely been reported to secrete insulin-growth factor II (IGF-II) and produce an enigmatic hypoglycemia. IGF-II-secreting sarcomas represent an extremely rare subset of soft tissue tumors, and reports are limited to a handful of cases.
PRESENTATION OF CASE: The authors present the case of hypoglycemia due to an IGF-II-secreting retroperitoneal sarcoma that was successfully treated by complete surgical resection. This report describes the diagnosis and management of this rare syndrome with 1-year follow-up and a review of the literature.
DISCUSSION: Steroid and growth hormone therapies also have efficacy to treat this hypoglycemia in some patients. However, outcomes appear better if combined with surgical resection.
CONCLUSIONS: The findings of this case report and review of the literature support a primary role for complete tumor resection to address tumor-induced hypoglycemia.
Jennifer A Hawasli; Jacob R Hopping; Eddy C Hsueh
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-11-11
Journal Detail:
Title:  International journal of surgery case reports     Volume:  5     ISSN:  2210-2612     ISO Abbreviation:  Int J Surg Case Rep     Publication Date:  2014 Nov 
Date Detail:
Created Date:  2014-12-1     Completed Date:  -     Revised Date:  2014-12-2    
Medline Journal Info:
Nlm Unique ID:  101529872     Medline TA:  Int J Surg Case Rep     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1225-1228     Citation Subset:  -    
Copyright Information:
Copyright © 2014. Published by Elsevier Ltd.
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