| Hypocholesterolaemic effects of Terminalia arjuna tree bark. | |
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MedLine Citation:
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PMID: 9080336 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Diet-induced hyperlipidaemic rabbits were given 50% ethanolic extract of Terminalia arjuna tree bark in doses of 100 mg/kg (Group B, n = 6) and 500 mg/kg (Group C, n = 6) and compared with controls (Group A). At 60 days of intervention in Groups A, B and C mean +/- S.E.M. total cholesterol was 574 +/- 61, 320 +/- 29 and 217 +/- 44 mg/dl, respectively (P < 0.01); LDL cholesterol was 493 +/- 57, 271 +/- 30 and 162 +/- 44 mg/dl (P < 0.01); HDL cholesterol was 59 +/- 7, 36 +/- 3 and 35 +/- 4 mg/dl (P = n.s.); triglyceride was 108 +/- 13, 67 +/- 6 and 101 +/- 26 mg/dl (P = n.s.); cholesterol/HDL ratio was 10.1 +/- 1.3, 9.2 +/- 1.1 and 6.1 +/- 1.0 (P = n.s.); and LDL/HDL ratio was 8.7 +/- 1.3, 7.8 +/- 1.1 and 4.5 +/- 1.0 (P < 0.01). The extract did not adversely affect biochemical tests of liver and renal function and haematological parameters. |
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Authors:
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A Ram; P Lauria; R Gupta; P Kumar; V N Sharma |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of ethnopharmacology Volume: 55 ISSN: 0378-8741 ISO Abbreviation: J Ethnopharmacol Publication Date: 1997 Feb |
Date Detail:
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Created Date: 1997-05-23 Completed Date: 1997-05-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7903310 Medline TA: J Ethnopharmacol Country: IRELAND |
Other Details:
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Languages: eng Pagination: 165-9 Citation Subset: IM |
Affiliation:
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Department of Pharmacology, S.M.S. Medical College, Jaipur, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cholesterol / blood Diet, Atherogenic Hypercholesterolemia / drug therapy* Kidney / drug effects Liver / drug effects Plant Extracts / pharmacology, therapeutic use Rabbits Trees* |
| Chemical | |
Reg. No./Substance:
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0/Plant Extracts; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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