| Hypocalcemic rickets and dilated cardiomyopathy: case reports and review of literature. | |
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MedLine Citation:
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PMID: 19387720 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Internationally, there have been isolated case reports published of children presenting with dilated cardiomyopathy (DCM) in the setting of undiagnosed rickets. Although there has been an increased prevalence of rickets in the United States, there has been only one documented case of associated DCM. At our institution, a hospital database search was conducted from year 1997 to year 2007 to identify patients with confirmed vitamin D deficiency in addition to DCM. Through this search, four exclusively breast-fed African American infants were identified. These infants presented with congestive heart failure secondary to DCM and, at their admission, were found to have laboratory evidence consistent with hypocalcemic rickets. These patients responded dramatically to treatment with vitamin D and calcium, and cardiac function returned to normal within months. Early recognition of vitamin D deficiency was an important factor in these patients' clinical course. These case reviews present a rare, serious complication of vitamin D-deficient rickets and support evidence for prevention of this nutritional deficiency with vitamin D supplementation in exclusively breast-fed infants. |
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Authors:
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Jennifer Brown; Susan Nunez; Melissa Russell; Christopher Spurney |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-04-23 |
Journal Detail:
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Title: Pediatric cardiology Volume: 30 ISSN: 1432-1971 ISO Abbreviation: Pediatr Cardiol Publication Date: 2009 Aug |
Date Detail:
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Created Date: 2009-07-27 Completed Date: 2009-11-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8003849 Medline TA: Pediatr Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 818-23 Citation Subset: IM |
Affiliation:
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Division of Pediatrics, Children's National Medical Center, 111 Michigan Avenue N.W, Washington, DC 20010, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Calcium
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blood* Cardiomyopathy, Dilated / diagnosis, etiology* Echocardiography, Doppler, Color Electrocardiography Female Follow-Up Studies Humans Hypocalcemia / blood, complications*, diagnosis Infant Male Rickets |
| Chemical | |
Reg. No./Substance:
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7440-70-2/Calcium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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