Document Detail

Hypocalcemia is common in the first 48 h of life in ELBW infants.
MedLine Citation:
PMID:  18598126     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The incidence of early hypocalcemia in extremely low birthweight (ELBW) infants is unknown because the distribution of serum calcium values in this population is not defined. OBJECTIVE: To determine the range of serum calcium values in ELBW infants during the first 48 h of life and the risks associated with low values. DESIGN/METHODS: Retrospective analysis of all ELBW infants admitted on day 1 of life from April 2004 to October 2006. Demographic variables, therapy, serum calcium (Ca), pH, albumin, and blood ionized Ca were recorded. RESULTS: There were 381 Ca levels obtained from 111 patients. Mean Ca was 6.90 mg/dL (1.73 mmol/L) (5(th)-95(th) percentile: 5.16-8.80). Ca levels rose after 24 h of life. Almost one quarter (23.1%) of the Ca levels were low by current standards. The majority of subjects (59.9%) had at least one hypocalcemic value. CONCLUSIONS: Serum Ca values are lower in ELBW infants and inconsequential. Thus, hypocalcemia should be re-defined for ELBW infants.
Khalid Altirkawi; Henry J Rozycki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  36     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  2008  
Date Detail:
Created Date:  2008-07-07     Completed Date:  2008-09-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  348-53     Citation Subset:  IM    
Division of Neonatal-Perinatal Medicine, Department of Pediatrics, Virginia Commonwealth University, Richmond, VA 23298-0276, USA.
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MeSH Terms
Blood Urea Nitrogen
Calcium / blood*
Cohort Studies
Creatinine / blood
Hydrogen-Ion Concentration
Hypocalcemia / blood*
Infant, Extremely Low Birth Weight / blood*
Infant, Newborn
Retrospective Studies
Serum Albumin / metabolism
Reg. No./Substance:
0/Serum Albumin; 60-27-5/Creatinine; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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