Document Detail

Hypobaric hypoxia on pulmonary wash fluid of rats.
MedLine Citation:
PMID:  6893755     Owner:  NLM     Status:  MEDLINE    
The biochemical appearance of the alveolar border pathology, whatever the origin of the impairment may be, has become most important. This is the reason why we have studied the influence of hypobaric hypoxia, at a pressure of 370 mm Hg, on the phospholipids of pulmonary surfactant and alveolar macrophages. During the first hours we observed a decrease in the phosphatidylcholines of the pulmonary surfactant and a concomitant increase in the lysocompounds with simultaneous appearance of a phospholipase activity which seemed to have a macrophage origin.
M C Prévost; C Vieu; L Douste-Blazy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Respiration; international review of thoracic diseases     Volume:  40     ISSN:  0025-7931     ISO Abbreviation:  Respiration     Publication Date:  1980  
Date Detail:
Created Date:  1981-02-19     Completed Date:  1981-02-19     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0137356     Medline TA:  Respiration     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  76-80     Citation Subset:  IM; S    
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MeSH Terms
Anoxia / metabolism*
Atmospheric Pressure
Fatty Acids / metabolism
Lung / metabolism*
Macrophages / metabolism
Phosphatidylcholines / metabolism
Phospholipids / metabolism
Pulmonary Alveoli / cytology
Pulmonary Surfactants / metabolism
Reg. No./Substance:
0/Fatty Acids; 0/Phosphatidylcholines; 0/Phospholipids; 0/Pulmonary Surfactants

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