| Hypnosis effect on carbon dioxide chemosensitivity. | |
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MedLine Citation:
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PMID: 3086046 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hypnosis is an induced state of heightened suggestibility during which certain physiologic variables can be altered. To investigate if carbon dioxide (CO2) chemosensitivity could be blunted during this suggestible state, we measured hypercapnic ventilatory response (HCVR, delta VE/delta PaCO2), oxygen consumption (VO2), breathing pattern (VT and f), inspiratory flow rate (VT/Ti), and inspiratory timing (Ti/Ttot) in 20 healthy subjects. Mouth occlusion pressures (P0.1) were measured in the last nine subjects. Resting oxygen consumption and minute ventilation were measured during awake and hypnotic control states. The HCVR was measured spontaneously and with the suggestion to maintain normal ventilation during both awake and hypnotic conditions. It was found that without a change in metabolism, ventilatory responses to CO2 could be blunted both voluntarily, and to a greater degree, with hypnotic suggestion. These findings may have important implications in clinical settings in which patients suffer from marked dyspnea secondary to increased ventilatory chemosensitivity. |
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Authors:
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P Sato; M Sargur; R B Schoene |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Chest Volume: 89 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 1986 Jun |
Date Detail:
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Created Date: 1986-07-16 Completed Date: 1986-07-16 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 828-31 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Carbon Dioxide / pharmacology* Female Heart Rate / drug effects Humans Hypercapnia / physiopathology Hypnosis* Male Middle Aged Oxygen Consumption / drug effects Pulmonary Ventilation / drug effects Respiration / drug effects* Rest Tidal Volume |
| Grant Support | |
ID/Acronym/Agency:
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HL-00906/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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